Dry eye symptoms are associated with poor mental health conditions, particularly mood, anxiety, and depression 1-5. Recent reports suggest that subjective dry eye symptoms are associated with increased anxiety and depression 4,5.


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  2. Wu M, Liu X, Han J, Shao T, Wang Y. Association Between Sleep Quality, Mood Status, and Ocular Surface Characteristics in Patients With Dry Eye Disease. Cornea 2018;38(3):311-7.
  3. Liang C-Y, Cheang W-M, Wang C-Y, Lin K-H, Wei L-C, Chen Y-Y, et al. The association of dry eye syndrome and psychiatric disorders: a nationwide population-based cohort study. BMC Ophthalmology 2020;20(1).
  4. Kitazawa M, Sakamoto C, Yoshimura M, Kawashima M, Inoue S, Mimura M, et al. The Relationship of Dry Eye Disease with Depression and Anxiety: A Naturalistic Observational Study. Translational Vision Science & Technology 2018;7(6):35.
  5. Bitar MS, Olson DJ, Li M, Davis RM. The Correlation Between Dry Eyes, Anxiety and Depression: The Sicca, Anxiety and Depression Study. Cornea 2019;38(6):684-9.